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1. NSAIDs (inflammation)

   NSAIDs have historically been classified according to their chemical composition, but as mechanism of action has come to the fore, this is also used to classify these drugs.

   NSAIDs within classes have similar characteristics and tolerability, with little difference in clinical efficacy at equivalent doses. The prescribers’ choice will be determined by other factors such as dosing regimens, route of administration and tolerability. For example, ibuprofen and diclofenac have half-lives of just 2–3 hours, whereas the oxicams have half-lives 10 times longer.

   efaccena - 09/09/2016 - 9:27am

2. NSAIDs for musculoskeletal conditions

   There are about 20 different nonsteroidal anti-inflammatory drugs (NSAIDs) available. Some, such as aspirin and ibuprofen, are widely available over-the-counter (OTC). Others are only available on prescription. NSAIDs are the most frequently used medicines for symptomatic relief in osteoarthritis (OA), the most common form of arthritis, and are often prescribed to rheumatoid arthritis (RA) patients.

   efaccena - 22/07/2016 - 8:25am